Characterization of Calpastatin Gene in Iranian Afshari Sheep

Presence of SNPs in GDF9 mRNA of Iranian Afshari Sheep

BACKGROUND Multiple births occur frequently in some Iranian sheep breeds, while infertility scarcely occurs. Mutation detection in major fecundity genes has been explored in most of Iranian sheep flocks over the last decade. However, previously reported single nucleotide polymorphisms (SNPs) for bone morphogenetic protein receptor-(BMPR)-1B and growth differentiation factor ) GDF9( known to aff...

Presence of SNPs in GDF9 mRNA of Iranian Afshari Sheep

presence of snps in gdf9 mrna of iranian afshari sheep

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study of bmp 15 gene in afshari and afshari × booroola merino cross sheep

introduction one of the most important sources of the red meat in iran is the meat produced from sheep. increasing lamb per ewe considered as a strategy for improving the efficiency for sheep production, although reproduction traits have low heritability. several genes associated with reproduction were investigated in the recent years. the bmp 15 gene and its paralog gdf 9 and receptor, bmpr-ib...

Investigation of GDF8 Gene Promoter in Iranian Sheep

Myostatin is a growth factor belonging to the TGFß superfamily. TGFß growth factors are active in the regulation of embryonic development and in tissue homeostasis in adults. Myostatin is a growth factor controlling proliferation of myoblasts in embryonic development. Mutations in coding sequences of the bovine myostatin (GDF8) gene lead to muscle hyperplasia suggesting its inhibitory function ...

Genetic Polymorphism of GDF9 Gene in Iranian Moghani Sheep Breed

The families of TGF-β proteins are the most important growth factors in the ovary for growth and differentiation of early ovarian follicles. Three related oocyte-derived members of the transforming growth factor-β superfamily namely growth differentiation factor 9 (GDF9), BMP15 and BMPR-IB have been shown to be essential for follicular growth and ovulation. Different mutations in the GDF9 gene ...